BIOCOM: High Tech High's biotechnology laboratory is based upon the support of BIOCOM. High Tech High students have participated in the annual BIO (Biotechnology Industry Organization) conference in the BioGENEius competition.

C.R.E.S.: The Center for Research of Endangered Species' Dr. Oliver Ryder and members of his laboratory have played a pivotal role in the initial spark and continued experimental refinement of bringing DNA to the classroom at High Tech High and DNA barcoding to address African bushmeat. An article detailing the initial kick-off intersession class was published in ZOONOOZ, written by Dr. Jay Vavra and Dr. Oliver Ryder.

Invitrogen Corporation: As a leader in life sciences through the research and development biotech supply company, their products allow a multitude of scientists to perform DNA technology. With the help of various academic grants from Invitrogen's biotechnology supplies, the students at High Tech High have been able to perform complex DNA sequencing procedure in-house at the BIOCOM Biotechnology Laboratory at the Gary and Jerri-Ann Jacobs High Tech High in San Diego.

The Jane Goodall Institute: Jane Goodall has directly contributed to some of the projects produced by members of this program. The institute carries the message that the power of the compassionate individual can make positive change on the environment and all living things. This message has been a key moral for the High Tech High Roots and Shoots club (which includes the every student under Dr. Jay Vavra).